MyBioSource.com's SH2D3A Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Immunohistochemistry. The SH2D3A Polyclonal Antibody was generated using NSP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
SH2D3A (SH2 domain containing 3A), also known as novel SH2-containing protein 1, is a 576 amino acid protein that is thought to play a role in JNK activation. SH2D3A interacts with p130 Cas and is found at low levels in fetal kidney, fetal lung, placenta, adult pancreas, kidney and lung. Subject to post-translational phosphorylation on multiple tyrosine residues, SH2D3A contains one Src homology 2 (SH2) domain. SH2 domains bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins